DMD – ANIMAL MODELS & PRECLINICAL TREATMENT

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Murine animal models for preclinical islet transplantation

Type 1 diabetes (T1D) is an autoimmune disease mediated by a combination of genetic and environmental triggers resulting in the lymphocytic infiltration of pancreatic islets with selective and progressive loss of the insulin-producing β cells. Even if over the years the autoimmune events have been well elucidated—at least in the mouse model—the etiology and pathogenesis of T1D involve poorly un...

متن کامل

Translational Animal Models of Atopic Dermatitis for Preclinical Studies



There is a medical need to develop new treatments for patients suffering from atopic dermatitis (AD). To improve the discovery and testing of novel treatments, relevant animal models for AD are needed. Generally, these animal models mimic different aspects of the pathophysiology of human AD, such as skin barrier defects and Th2 immune bias with additional Th1 and Th22, and in some populations T...

متن کامل

Criteria for valid preclinical trials using animal stroke models.

Stroke welcomes Letters to the Editor and willpublish them, if suitable, as space permits. They should not exceed 1,000 words (excluding references) and may be subject to editing or abridgment. Please submit Letters to the Editor in duplicate, typed double-spaced. Include an appropriate title and a fax number for the corresponding author. The American Heart Association requires that all authors...

متن کامل

Animal Models for Basic and Preclinical Research in Bladder Cancer

Bladder cancer is one of the most common cancers in the world. In 2006, there were about 61,240 diagnosed cases of bladder cancer and approximately 13,060 deaths attributable to this disease, being the prevalence estimated worldwide more than 1,000,000 patients (Jemal et al., 2006; Lerner, 2005). Taking into account that its incidence seems to be increasing, bladder cancer is clearly a signific...

متن کامل

The current state of preclinical prostate cancer animal models.

Prostate cancer continues to be a major cause of morbidity and mortality in men around the world. The field of prostate cancer research continues to be hindered by the lack of relevant preclinical models to study tumorigenesis and to further development of effective prevention and therapeutic strategies. The Prostate Cancer Foundation held a Prostate Cancer Models Working Group (PCMWG) Summit o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Neuromuscular Disorders

سال: 2020

ISSN: 0960-8966

DOI: 10.1016/j.nmd.2020.08.209